Oncologists choose what course of treatment to pursue for each patient. There are many options. There is no regular treatment course for malignant mesothelioma patients. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.
While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) All three methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.
The mesothelial tissue around the tumor is removed by surgery. It is a grueling surgery with unknown benefits to patients. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.
The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.




